Bold = Duncan lab members
* Corresponding author
Preprints
* Corresponding author
- Zdouc, M. M., Blin, K., Louwen, N. L. L., Navarro, J., Loureiro, C., Bader, C. D., Bailey, C.B., Barra, L., Booth, T. J., Bozhüyük, K. A. J., Cediel-Becerra, J. D. D., Charlop-Powers, Z., Chevrette, M. G., Chooi, Y. H., D’agostino, P. M., de Rond, T., Del Pup, E., Duncan, K. R.,…[…Fetter, A., Macias, M. I.,…]… Linington, R. G., Weber, T., Medema, M. H. (2024) MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration. Nucleic Acids Research. 53(D1), D678–D690 https://doi.org/10.1093/nar/gkae1115
- Poynton, E. F., van Santen, J. A., Pin, M., Macias, M., McMann, E., Parra, J., Showalter, B., Zaroubi, L., Duncan, K. R., Linington, R. G. (2024) The Natural Products Atlas 3.0: extending the database of microbially derived natural products. Nucleic Acids Research. 53(D1), D691-D699 https://doi.org/10.1093/nar/gkae1093
- Whatmough, B., Holmes, N. A., Wilkinson, B, Hutchings, M. I., Parra, J., Duncan, K. R.* (2024) Microbe Profile: Pseudonocardia: antibiotics for every niche. Microbiology. 170(9) https://doi.org/10.1099/mic.0.001501
- Parra, J., Jarmusch, S. A., Duncan, K. R.* (2024) Multi-omics analysis of antagonistic interactions among free-living Pseudonocardia from diverse ecosystems. Env. Micro. Accepted (May 2024).
- Hughes, A. H and Duncan, K. R.* (2024) Eliciting specialized metabolites from marine microalgae using abiotic stress. Applied Phycology. 5(1), 1-11. https://doi.org/10.1080/26388081.2023.2280928
- Parra, J., Beaton, A., Seipke, R. F., Wilkinson, B., Hutchings, M. I., Duncan, K. R.* (2023) Antibiotics from rare actinomycetes, beyond the genus Streptomyces. Curr. Op. Micro. 76 (102385) https://doi.org/10.1016/j.mib.2023.102385
- Mullowney,M. W,* Duncan, K. R.*, Elsayed, S. S.*, Garg, N.*, van der Hooft, J. J. J.*, Martin, N. I*., Meijer, D*., Terlouw, B*. R., Biermann, F., Blin, K., Durairaj, J., Gorostiola González, M., Helfrich, E. J. N., Huber, F., Leopold-Messer, S., Rajan, K., de Rond, T., van Santen, J. A., Sorokina, M., Balunas, M. J., Beniddir, M. A., van Bergeijk, D. A., Carroll, L. M., Clark, C. M., Clevert, D., Dejong, C. A., Du, C., Ferrinho,S.,Grisoni, F., Hofstetter, A., Jespers, W., Kalinina, O. V., Kautsar, S. A., Kim, H., Leao, T. F., Masschelein, J., Rees, E. R., Reher, R., Reker, D., Schwaller, P., Segler, M., Skinnider, M. A., Walker, A. S., Willighagen, E. L., Zdrazil, B., Ziemert, N., Goss, R. J. M., Guyomard, P., Volkamer, A., Gerwick, W. H., Kim, H. U., Müller, R., van Wezel, G. P., van Westen, G. J. P., Hirsch, A. K. H., Linington, R. G., Robinson, S. L., Medema M. H. (2023) Artificial intelligence for natural product drug discovery. Nature Reviews Drug Discovery. 1-22. https://doi.org/10.1016/j.mib.2023.102385 *co-first author
- Domingo-Roca, R., Lasserre, P., Riordan, L., Macdonald, A.R., Dobrea, A., Duncan, K.R., Hannah, S., Murphy, M., Hoskisson, P.A. and Corrigan, D.K. (2023) Rapid assessment of antibiotic susceptibility using a fully 3D-printed impedance- based biosensor. Biosensors and Bioelectronics X, 13. 100308. https://doi.org/10.1016/j.biosx.2023.100308
- Terlouw, B. R., Blin, K., Navarro-Muñoz, J. C., Avalon, N., Chevrette, M. G., Egbert, S., Lee, S., Meijer, D., Recchia, M. J. J., Reitz, Z. L., van Santen, J. A., Selem-Mojica, N., Tørring, T., Zaroubi, L., Alanjary, M., Aleti, G., Aguilar, C.,.[…] Duncan, K. R.,[….] Collemare, J., Linington, R. G., Weber, T and Medema, M. H. (2023) MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters. Nucleic Acids Research. 51(D1), D603-D10. https://doi.org/10.1093/nar/gkac1049
- Dunphy, R. D., Lassere, P., Riordan, L., Duncan, K. R., McCormick, C., Murray, P. and Corrigan, D. (2022) Combining Hyperspectral Imaging and Electrochemical Sensing for Detection of Pseudonomcas aeruginosa through Pyocyanin Production. RSC Sens. Diagn. 1. 841-850. https://doi.org/10.1039/D2SD00044J
- Feeney, M. A., Newitt, J. T... [...]. Duncan, K. R.*, Fernandez, L. T.*, Hutchings, M. I.* (2022) ActinoBase: An Actinomycete Community Wiki. Microbial Genomics. 8(7). http://doi.org/10.1099/mgen.0.000824 [Invited paper (with Hutchings, JIC) by journal editors].
- Hutchings, M. I. and Duncan, K.R * (2022). Overcoming drug resistance, the natural way. Cell Host & Microbe, 30(3), 273-274. https://doi.org/10.1016/j.chom.2022.02.008
- Van Santen, J. A., Poyton, E. F., Iskakova, D., McMann, E., Alsup, T. A., Clark, T. N., Fergusson, C. H., Fewer, D. P., Hughes, A. H., McCadden, C. A., Parra, J., Soldatou, S., Rudolf, J. D., Janssen, E. M. L., Duncan, K. R. Linington, R. G. (2022) The Natural Products Atlas 2.0: a Database of Microbially-derived Natural Products. Nucleic Acid Research., 50(D1), D1317-D1323. http://doi.org/10.1093/nar/gkab941
- Parra, J., Soldatou, S., Rooney, L. M., Duncan, K. R.* (2021) Psudonocardia abyssalis sp. nov. and Pseudonocardia oceani sp. nov. Two Novel actinomycetes Isolated from the Deep Southern Ocean. IJSEM., 71(9), 005032. https://doi.org/10.1099/ijsem.0.005032
- Schorn, M.A., Verhoeven, S., Ridder, L […] Duncan, K. R., Crüsemann, M., Rogers, S., Dorrestein, P. C., Medema, M. H., van der Hooft, J. J. J. (2021) A Community Resource for Paired Genomic and Metabolomic Data Mining. Nat. Chem. Biol., 17(4), 363-368. https://doi.org/10.1038/s41589-020-00724-z
- Soldatou, S., Eldjarn, G. H., Ramsey, A., van der Hooft, J. J. J., Hughes, A. H., Rogers, S. & Duncan, K. R* (2021) Comparative Metabologenomics Analysis of Polar actinomycetes Marine Drugs, 19(2), 103-124. https://doi.org/10.3390/md19020103
- Hughes, A. H., Magot, F., Tawfike, A., Rad-Menéndez, C., Thomas, N., Young, L. C., Stucchi, L., Carettoni, D., Stanley, M. S., Edrada-Ebel, R. & Duncan, K. R.* Exploring the Chemical Space of Macro- and Micro-algae Using Comparative Metabolomics. (2021) Microorganisms. 9(2), 311-327. http://doi.org/10.3390/microorganisms9020311
- Eldjarn, G.H., Ramsay, A. van der Hooft, J. J. J. Duncan, K. R. Soldatou, S., Rousu, J., Daly, R., Wandy, J., Rogers, S.*. (2020). Ranking Microbial Metabolomic and Genomic Links in the NPLinker Framework Using Complementary Scoring Functions. PLoS Comput. Biol. 17(5): e1008920. https://doi.org/10.1371/journal.pcbi.1008920
- van der Hooft, J. J., Mohimani, H., Bauermeister, A., Dorrestein, P. C., Duncan, K. R.*, Medema, M. H.* (2020) Linking Genomics and Metabolomics to Chart Specialized Metabolite Discovery. Chem. Soc. Rev., 49, 3297-3314. https://doi.org/10.1039/D0CS00162G
- van Santen, J. A., Jacob, G., Singh, A. L., Aniebok, V., Balunas, M. J., Bunsko, D., Neto, F. C., Espriu, L. C., Chang, C., Clark, T. N., Little, J. L. C., Delgadillo, D. A., Dorrestein, P. C., Duncan, K. R., Egan, J. M., Galey, M. M., Haeckl, F. P. J., Hua, A., Hughes, A. H., Iskakova, D., Khadilkar, A., Lee, J-H., Lee, S., LeGrow, N., Liu, D. Y., Macho, J. M., McCaughey, C. S., Medema, M. H., Neupane, R. P., O’Donnell, T. J., Paula, J. S., Sanchez, L. M., Shaikh, A. F., Soldatou, S., Terlouw, B. R.,Tran, T. A., Valentine, M., van der Hooft, J. J. J., Vo, D. A., Wang, M., Wilson, D., Zink, K. E. and Linington, R. G. (2019) The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery. ACS Central Science. 5(11), 1824-1833. http://doi.org/10.1021/acscentsci.9b00806
- Sebak, M., Saafan, A. E., AbdelGhani, S., Bakeer, W., El-Gendy, A. O., Espriu, L., Duncan, K. R., Edrada-Ebel, R.* (2019) Bioassay- and Metabolomics-guided Screening of Bioactive Soil actinomycetes from the Ancient City of Ihnasia, Egypt. PLOS One. 15(2): e0228901. http://doi.org/10.1371/journal.pone.0226959
- Millán-Aguiñaga, N., Soldatou, S., Brozio, S., Munnoch, J. T., Howe, J., Hoskisson, P. A., Duncan, K. R.* (2019) Awakening Ancient Polar Actinobacteria: Diversity, Evolution and Specialized Metabolite Potential. Microbiology 165. 1169-1180. http://doi.org/10.1099/mic.0.000845
- Soldatou, S., Eldjarn, G. H., Huerta-Uribe, A., Rogers, S. and Duncan, K. R.* (2019) Linking Biosynthetic and Chemical Space to Accelerate Microbial Secondary Metabolite Discovery. FEMS Microbiology Letters. 336(12), Fnz142. https://doi.org/10.1093/femsle/fnz142
- Hicks, N. Liu, X, Gregory, R., Kenny, J., Lucaci, A., Lenzi, L, Paterson, D. M. and Duncan, K. R.* (2018) Temperature Driven Changes in Benthic Bacterial Diversity Influences Biogeochemical Cycling in Coastal Sediments Front. Microbiol. 9, 1730. https://doi.org/10.3389/fmicb.2018.01730
- Vallet, M., Vanbellingen, Q. P. F., T., Le Caer, J-P., Della-Negra, S., Touboul, D., Duncan, K. R., Nay, B., Brunelle, A. and Prado, S. (2017) An Integrative Approach to Decipher the Chemical Antagonism Between the Competing Endophytes Paraconiothyrium variabile and Bacillus subtilis. J. Nat. Prod. 22, 80 (11), 2863-2873. https://doi.org/10.1021/acs.jnatprod.6b01185
- Wang, M., Carver, J. J., Phelan, V. V., Sanchez, L. M., Garg, N., Peng, Y., Nguyen, D. D., Watrous, J., Kapono, C. A., Luzzatto-Knaan, T., Porto, C., Bouslimani, A., Melnik, A. V., Meehan, M. J., Liu, W- T., Crüseman, M., Boudreau, P. D., Esquenazi, E., Sandoval-Calderón, M., Kersten, R. D., Pace, L. A., Quinn, R. A., Duncan, K. R., Hsu, C-C., Floros, D. J., Gavilan, R. G., Kleigrewe, K., Northen, T., Dutton, R. J., Parrot, D., Carlson, E. E., Aigle, B., Michelsen, C. F., Jelsbak, L., Sohlenkamp, C., Pevzner, P., Edlund, A., McLean, J., Piel, J., Murphy, B. T., Gerwick, L., Liaw, C-C., Yang, Y-L., .... Mascuch, S. J., Tomasi, S., Jenkins, S., Macherla, V., Hoffman, T., Agarwal, V., Williams, P. G., Dai, J., Neupane, R., Gurr, J., Rodríguez, A. M. C., Lamsa, A., Zhang, C., Dorrestein, K., Duggan, B. M., Almaliti, J., Allard, P, M., Phapale, P., Nothias, L. F., Alexandrov, T., Litaudon, M., Wolfender, J. L., Kyle, J. E., Metz, T. O., Peryea, T., Nguyen, D-T., VanLeer, D., Shinn, P., Jadhav, A., Müller, R., Waters, K. M., Shi, W., Liu, X., Zhang, L., Knight, R., Jensen, P. R., Palsson, B. O., Pogliano, K., Linington, R. G., Gutiérrez, M., Lopes, N. P., Gerwick, W. H., Moore, B. S., Dorrestein, P. C. Bandeira, N. (2016) Sharing and Community Curation of Mass Spectra by GNPS. Nature Biotechnology. 34, 828–837. https://doi.org/10.1038/nbt.3597
- Buchholtz, H. and Duncan, K. R.* (2016) Antarctic Sponge Associated Microbial Chemistry with Biomedical Relevance. Current Organic Chemistry 21(5), 395-401. https://doi.org/ 10.2174/1385272820666161020122153 Role: designed and led study, manuscript writing and editing.
- Purves, K., MacIntyre, L., Brennan, D., Hreggviosson, G. O., Kuttner, E., Asgeirsdottir, M. E., Young, L. C., Green, D. H. Edrada-Ebel, R, Duncan, K.R.* (2016) Using Molecular Networking for Microbial Secondary Metabolite Bioprospecting. Metabolites 6(1): 2. https://doi.org/10.3390/metabo6010002
- Duncan, K.R.$, Crüsemann, M. $, Lechner, A.$, Sarkar, A., Li, J., Ziemert, N., Wang, M., Moore, B. S., Dorrestein, P. C., Jensen, P. R. (2015) Molecular Network and Pattern-Based Genome Mining Improves Discovery of Biosynthetic Gene Clusters and their Products from Salinispora Species. Chem. & Biol. (now named Cell Chemical Biology) 22: 1-12. https://doi.org/10.1016/j.chembiol.2015.03.010 $ co-first author.
- Patin, N.V., Duncan, K.R., Jensen, P. R. (2015) Competitive Strategies Differentiate Closely-Related Species of Marine Bacteria. ISME J. 10(2): 478-490. https://doi.org/10.1038/ismej.2015.128
- Duncan, K., Haltli, B., Gill, K.A., Kerr R.G. (2014) Bioprospecting from Marine Sediments of New Brunswick, Canada: Exploring the Relationship Between Total Bacterial Diversity and Actinobacteria Diversity. Mar. Drugs, 12, 899-925. https://doi.org/10.3390/md12020899
- Duncan, K. R., Haltli, B., Gill, K. A., Correa, H., Berrué, F., Kerr, R. G. (2014) Exploring the Diversity and Metabolic Potential of Actinomycetes from Temperate Marine Sediments from Newfoundland, Canada. J. Ind. Microbiol. Biotech 42(1), 57-72. https://doi.org/10.1007/s10295-014-1529-x
- Weitz, M., Duncan, K., Patin, N. V., Jensen, P. R. (2013) Antagonistic Interactions Mediated by Marine Bacteria, the Role of Small Molecules. J. Chem. Ecol. 39(7), 879- 891. https://doi.org/10.1007/s10886-013-0316-x
- Forner, D., Berrue, F., Correa, H., Duncan, K., Kerr, R. G. (2013) Chemical Dereplication of Marine Actinomycetes by Liquid Chromatography - High Resolution Mass Spectrometry Profiling and Statistical Analysis Anal. Chim. Acta. 12 (805), 70-79. https://doi.org/10.1016/j.aca.2013.10.029
Preprints
- Riordan, L., Lassere, P., Dorrigan, D., Duncan, K.R.* (2024) Quantification of Pseudomonas aeruginosa biofilms using electrochemical methods. Access Microbiology 00906v.1 https://doi.org/10.1099/acmi.0.000906.v1
- Metz, T. O., Adkins, J. N., Armentrout, P. B., Chain, P., Chu, F., Corley, C. D., Cort, J. R., Denis, E., Drell, D., Duncan, K. R., Ewing, R. G., Fernandez, F. M., Fiehn, O., Garg, N., Grimme, S., Henry, C., Hettich, R. L., Kind, T., Linington, R. G., Miller, G. W., Northen, T., Overdahl, K., Patrinos, A., Raftery, D., Rigor, P., Smith, R. D., Sobus, J., Teeguarden, J., Vertes, A., Waters, K., Webb-Robertson, B-J., Williams, A., Wishart, D. (2023) Decoding the molecular universe – workshop report. ArXiv (November 2023) https://doi.org/10.48550/arXiv.2311.11437